ea0026p328 | Obesity | ECE2011
Loves S
, de Jong J
, van Sorge A
, Telting D
, Hermus A
, de Boer H
Introduction: Hypogonadotropic hypogonadism is frequently observed in morbidly obese men, due to aromatase-dependent conversion of androgens to estrogens. The clinical impact of this sex hormone imbalance is unknown.Aim: Evaluate the clinical effects of aromatase inhibition in obesity-related hypogonadism.Methods: Double-blind, placebo-controlled, 6-month trial in severely obese men (BMI>35 kg/m2) with obesity-relate...